ProstateProstate research is a focus area for several Pathology faculty members. This research addresses knowledge gaps in prostate cancer prevention, prognostic biomarkers of aggressive cancers and understanding of potential therapeutic targets. Our translational approach to research maintains clinical relevance and focus on the prostate cancer patient, while also utilizing in vitro and in vivo models to reveal molecular mechanisms. Funded projects range from clinical trials to molecular next-generation sequencing.

Prostate_Cancer_Diag

Maarten C. Bosland, DVSc, PhD

Prostate cancer chemoprevention
Hormonal carcinogenesis of the prostate & endocrine disruptors

Anjen Chenn, MD, PhD

Diagnostic test/assay discover and development

Alan M. Diamond, PhD

The role of anti-oxidant proteins in prostate cancer etiology
The molecular and biological consequences of allelic variations in the genes for selenium-containing proteins

Peter H. Gann, MD, ScD

Prostate cancer biomarker development
Molecular epidemiology of prostate cancer
Digital microscopy and image analysis for prostate cancer prognosis

Andre Kajdacsy-Balla, MD, PhD 

Prostate cancer clinical outcomes prediction methods
The effect of environmental agents on prostate cancer progression and metastasis

Larisa Nonn, PhD

Zinc homeostasis alterations in prostate carcinogenesis
microRNAs as prognostic markers of cancer aggressiveness in patient blood
Vitamin D and prostate health and cancer prevention
In vitro models of prostate cell biology

Gail S. Prins, PhD

Prostate development and early-life reprogramming by hormones and endocrine disrupting chemicals
Prostate stem cells
Hormonal prostate carcinogenesis

Virgilia Macias, MD

Prognostic markers in prostate cancer