‚ÄčNonn

Larisa Nonn, PhD
Associate Professor
phone: (312) 996-0194
fax: (312) 996-4812
email: Inonn@uic.edu
website:http//nonnlab.pathology.uic.edu/

 

 

 

Research Areas

  • Prostate cancer
  • Prognostic markers in patient blood
  • In vitro models of prostate cell biology

What I Do

The focus of my lab is prostate cancer research and there are several projects aimed at examining several questions.

  • How does microRNA regulation and the anti-inflammatory actions of vitamin D contribute to prevention of prostate carcinogenesis? Do these actions of vitamin D contribute to the prostate cancer disparities? 

  • Does the oncogenic activity of the miR-183 family cluster require zinc regulation in prostate epithelial cells? 

  • Are there microRNAs in the serum of prostate cancer patients that provide prognostic information about the tumor

Biography

I received my BS degree in Molecular Biology from the University of Wisconsin at Madison. During that time I researched tamoxifen metabolism in the lab of Dr. Henry Pitot and chaperone proteins in Dr. Betty Craig’s lab.  My PhD research focused on mitochondrial redox control and was done under the mentorship of Dr. Garth Powis at the University of Arizona. I went on to research the anti-inflammatory activity of vitamin D in primary human prostate cells during my postdoctoral training at Stanford University under the guidance of Dr. Donna Peehl.

All of this training landed me in the Department of Pathology at the University of Illinois at Chicago-UIC. Here at UIC I have maintained a research focus on prostate cancer and vitamin D. The research in my lab has grown to include microRNAs, zinc homeostasis in the prostate as well as analysis of clinical trial patient specimens to validate in vitro findings.

Education

B.S. Molecular Biology, University of Wisconsin at Madison
Ph.D. Pharmacology/Cancer Biology, University of Arizona

Fellowship

Postdoctoral Fellow, Stanford University Department of Urology

Research Expertise

I am a prostate cancer researcher with research expertise is in vitamin D, microRNAs, zinc homeostasis and in vitro models of prostate cell biology.

Awards and Honors

  • 2013       Departmental Faculty of the Year, UIC College of Medicine
  • 2013       American Urological Association, Showcase for Young Investigators
  • 2012       Society for Basic Urologic Research Young Investigator Award. These awards are given to
                   recognize researchers under the age of 40 who have made significant contribution to
                   urologic research
  • 2012        American Cancer Society Research Scholar
  • 2011        Travel Award, Department of Defense, Innovative Minds in Prostate Cancer Today
                    (IMPaCT) meeting
  • 2007        Publication selected for the 2006 issue of the Annual Bibliography of Significant Advances
                    in Dietary Supplements Research by the Office of Dietary Supplements at the National
                    Institutes of Health
  • 2007        Travel Award, Department of Defense, Innovative Minds in Prostate Cancer Today
                    (IMPaCT) meeting
  • 2006        Packard Award for the Best Urology Postdoctoral Publication, Stanford College of Medicine
  • 2005-06   Chief Postdoctoral Fellow, Department of Urology, Stanford College of Medicine 
  • 2004        Scholar in Training Award, American Association for Cancer Research
  • 2004        Prostate Cancer Postdoctoral Researcher Grant, Department of Defense
  • 2003        Endocrinology Postdoctoral NIH Training Grant, Stanford University
  • 2003        Postdoctoral Research Scholar Award, American Foundation for Urologic Disease

Selected Recent Publications

Click to View Recent Publications

Keywords

Prostate cancer, microRNAs, vitamin D