Alan M. Diamond, PhD
- B.S., Biology, 1978 - Brooklyn College, Brooklyn, New York
Ph.D., Biochemistry, 1982 - SUNY at Stony Brook, New York
- Post-Doctoral Fellowship, 1982-1986 - Harvard Medical School and Dana Farber Cancer Institute, Boston, MA.
- Research Focus
- Anti-oxidant proteins and cancer etiology
Functions of selenium-containing proteins
The impact of naturally occurring genetic variations on health
- Selected Recent Publications
Ansong, E., Yang, W, and Diamond, A.M. Molecular cross-talk between members of distinct families of selenium containing proteins. Mol. Nutr. Food Res. 58:117-123, 2014.
Renike, E.N., Ekoue, D.N., Bera, S., Mahmud, N. and Diamond, A.M. Translational regulation of GPx-1 and GPx-4 by the mTOR pathway. PLOS One 9:393472, 2014
Ozten, N., Schlicht, M., Diamond, A.M. and Bosland, M.C .L-Selenomethionine does not protect against testosterone plus 17β-estradiol-induced oxidative stress and preneoplastic lesions in the prostate of NBL rats. Nutr Cancer.66:825-34, 2014
Bera, S., Weinberg, F., Ekoue, D.N., Ansenberger-Fricano, K., Mao, M., Bonini, M.G. and Diamond, A.M. Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function. Cancer Res. 74:5118-26, 2014
Renike, E.N., Bera, S. and Diamond, A.M Exposure of CML Cells to Imatinib Results in the Post-Transcriptional Induction of Manganese Superoxide Dismutase. Leuk Lymphom. 19:1-4, 2014
Ekoue, D.N. and Diamond A.M. It takes two anti-oxidants to tango: the interaction between manganese superoxide dismutase and glutathione peroxidase-1. Turk J. Biol. 38:748-753, 2014.
Hart, P.C, Ansenberger-Fricano, K., Mao, M., , Luelsdorf de Abreu, A., Ekoue, D.N., Ganini,D., Kajdacsy-Balla, A., Diamond, A.M., Minshall, R.D., Consolaro, M.E.L., Santos, J.H., Bonini, M.G. SOD2 upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signaling in cancer. Nature Communications, 2015 Feb 5;6:6053. doi: 10.1038/ncomms7053
Ying, Q., Ansong, E., Diamond, A.M. and Yang, W. Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 are associated with metabolic pathways PLOS , 10:e0126285, 2015
Diamond, A.M. The subcellular location of selenoproteins and the impact on their function, Nutrients, 7:3938-3948, 2015
Ansong, E., Ying, Q., Ekoue, D.N., Deaton, R., Kajdacsy-Balla, A., Yang, W., Gann, P.H and Diamond, A.M. Evidence for Selenium Binding Protein 1 as a Tumor Suppressor in Prostate Cancer. PLoS One. 2015 May 18;10(5):e0127295